Nine young pigs were depancreatized, the average survival being 9 days. Although ingested carbohydrate was quantitatively excreted, the fasting glucose excretion was slight or absent, and the fasting N excretion was low. Ketonuria was marked but was not accompanied by severe acidosis. Injection of pituitary extracts produced acidosis, coma and greatly increased serum lipoids. The results are compared with pancreatic diabetes in other species and with the findings in hypophysectomized or adrenalectomized diabetic animals. The seemingly mild diabetes of the pig may be due to the nature of its pituitary (or other endocrine) function rather than to the utilization of carbohydrate in the absence of insulin.