Ein neues kristallinisches Serumglobulin II

Abstract

Holmberg and Gronwall discovered a new crystalline serum globulin II in the blood of a patient suffering from arthritis (Hoppe-Seyler''s Zeitschr. physiol. Chem., 273: 199, 1942). The patient was readmitted to the hospital and the crystalline globulin was present in her blood in the same conc. as previously. Her Wassermann reaction had changed from positive to negative. Crystallization of the globulin was prevented if the blood was taken under oil or if CO2 was passed through it. If the CO2 tension was decreased by passing air through the blood, the globulin was promptly obtained in crystalline form, and could not be made to redissolve by again passing CO2 through the blood. The new serum globulin contained about 7% tryptophane, while normal serum globulin contains 5.5%.