Value of electron microscopy in cytologic diagnosis of fine-needle biopsy
- 1 June 1983
- journal article
- research article
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 140 (6), 1253-1258
- https://doi.org/10.2214/ajr.140.6.1253
Abstract
Fine-needle biopsy in 14 consecutive patients with suspected malignancies were evaluated by routine cytology and electron microscopy. A protocol is described in which material from fine-needle biopsy can be held in glutaraldehyde and later processed for electron microscopy if necessary. Adequate tissue for electron microscopy was obtained in 12 of 14 cases. Specific classification of the tumor cells in these cases was achieved through electron microscopy. In six cases electron microscopy provided a more certain diagnosis than cytology alone. In two cases electron microscopy had significant impact on diagnosis and clinical management. The opportunity to examine tissues with electron microscopy increased the utility and specificity of the fine-needle technique without adding to patient discomfort or the cost of a second procedure.This publication has 3 references indexed in Scilit:
- Transthoracic needle aspiration biopsy: accuracy of cytologic typing of malignant neoplasmsAmerican Journal of Roentgenology, 1981
- Comparative Histopathologic, Histochemical, Electron Microscopic and Tissue Culture Studies of Bronchial Carcinoids and Oat Cell Carcinomas of LungAmerican Journal of Clinical Pathology, 1978
- DIFFUSE NEUROENDOCRINE SYSTEM AND APUD CONCEPT - RELATED (ENDOCRINE) PEPTIDES IN BRAIN, INTESTINE, PITUITARY, PLACENTA, AND ANURAN CUTANEOUS GLANDS1977