Perceptions and Experiences of Patients Receiving Oral Chemotherapy
- 1 August 2010
- journal article
- Published by Oncology Nursing Society (ONS) in Clinical Journal of Oncology Nursing
- Vol. 14 (4), 447-53
- https://doi.org/10.1188/10.cjon.447-453
Abstract
Although many patients prefer orally administered cancer therapy (including oral chemotherapy) because of its convenience, the shift from hospital to home-based administration creates concerns. This article explores the perceptions and experiences of oral chemotherapy users and their caregivers to assess vulnerabilities and improvement opportunities at each stage of the medication process: choosing oral chemotherapy, prescribing, dispensing, administering, and monitoring. The authors recruited 15 current and former oral chemotherapy users, as well as caregivers who administered the medications to children, to participate in one of two focus group sessions at a comprehensive cancer center. Participants largely were satisfied with oral cancer therapy but raised concerns regarding their lack of preparedness for side effects and their unfamiliarity with the possible techniques to mitigate drug toxicity. Participants also described difficulties obtaining medications through retail pharmacies. Parents of pediatric patients with cancer indicated concerns regarding their children's emotional health and correct medication administration. Participants believed that the initial prescribing encounter should have included more education, and they also wanted more frequent follow-up by healthcare practitioners. As oral cancer therapy is used more widely, oncology healthcare providers will need to create robust mechanisms to support their safe use.Keywords
This publication has 16 references indexed in Scilit:
- Overview of the changing paradigm in cancer treatment: Oral chemotherapyAmerican Journal of Health-System Pharmacy, 2007
- Safe Administration of Oral ChemotherapyClinical Journal of Oncology Nursing, 2003
- Multicenter Phase III Study of Uracil/Tegafur and Oral Leucovorin Versus Fluorouracil and Leucovorin in Patients With Previously Untreated Metastatic Colorectal CancerJournal of Clinical Oncology, 2002
- First-line oral capecitabine therapy in metastatic colorectal cancer: a favorable safety profile compared with intravenous5-fluorouracil/leucovorinAnnals Of Oncology, 2002
- Patient preference and pharmacokinetics of oral modulated UFT versus intravenous fluorouracil and leucovorinEuropean Journal Of Cancer, 2002
- Oral vinorelbine: Feasibility and safety profileAnnals Of Oncology, 2001
- Answering Patients' Needs: Oral Alternatives to Intravenous TherapyThe Oncologist, 2001
- Comparison of Oral Capecitabine Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Treatment in 605 Patients With Metastatic Colorectal Cancer: Results of a Randomized Phase III StudyJournal of Clinical Oncology, 2001
- Patient noncompliance with self-administered chemotherapyCancer, 1990
- Compliance with oral drug therapy in patients with hematologic malignancy.Journal of Clinical Oncology, 1987