A new 5′‐non‐coding region for human placental insulin‐like growth factor II mRNA expression

Abstract
A human placenta cDNA library was screened for insulin‐like growth factor II (IGF‐II). Four clones were selected, which exhibited an IGF‐II cDNA coding sequence identical to those previously described for human adult liver IGF‐II cDNA. Extensive sequence diversity was observed in the 5′‐non‐coding region, probably resulting from differential intron splicing.