Hemicholinium-3: Noncholinergic Effects on Squid Axons
- 21 February 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 163 (3869), 820-821
- https://doi.org/10.1126/science.163.3869.820
Abstract
Hemicholinium-3, when applied to the inside of a squid axon, is effective in blocking the action potential. This action is not antagonized by the addition of choline or acetylcholine to the perfusate. Voltage-clamp experiments show that hemicholinium-3 depresses both the early transient and late steady-state components of membrane ionic conductances, with a greater effect on the peak transient component.Keywords
This publication has 6 references indexed in Scilit:
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