The effect of cardioacceleration by right atrial pacing on myocardial blood flow in normal human subjects

Abstract

The myocardial blood flow response (MBF), measured by a coincidence counting technique and ⁸⁴RbCl, to cardioaccleration by right atrial pacing, was studied in 18 normal subjects. MBF was found to increase at approxmately 130 beats/min but decreased at more rapid rates (150 beats/min). Further study will be required to resolve the problem of this narrow range of response in order to validate pacing studies in the evaluation of serial changes in coronary reserve.