Effect of Diethyldithiocarbamate on the Respiration of Active and Blocked Embryonic Cells.

Abstract

Na diethyldithiocarbamate did not significantly affect the O2 consumption of mitotically active and blocked embryonic cells of the embryo of the grasshopper, Melanoplus differentialis. In general diethyldithiocarbamate produces stimulation in low doses and in high doses an initial inhibition followed by a marked stimulation in the O2 intake of embryonic cells. Partial recovery from high initial doses of the reagent occurs. Copper salts are markedly antagonized when in the presence of the carbamate.