Platelet Activation and Atherothrombosis
Top Cited Papers
- 13 December 2007
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 357 (24), 2482-2494
- https://doi.org/10.1056/nejmra071014
Abstract
This review of the role of platelets in atherothrombosis illuminates the surprisingly numerous activities of these tiny, anucleate cells and stresses their participation in the inflammatory component of atherothrombosis. The information is presented in the context of the prevention of atherothrombosis by antiplatelet agents now in clinical use.Keywords
This publication has 106 references indexed in Scilit:
- mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human plateletsBlood, 2006
- Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human plateletsThe Journal of Experimental Medicine, 2006
- Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trialsBMJ, 2006
- Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular functionJCI Insight, 2006
- Adventures in vascular biology: a tale of two mediatorsPhilosophical Transactions Of The Royal Society B-Biological Sciences, 2006
- Inflammation, Atherosclerosis, and Coronary Artery DiseaseNew England Journal of Medicine, 2005
- A Critical Role of Platelet Adhesion in the Initiation of Atherosclerotic Lesion FormationThe Journal of Experimental Medicine, 2002
- Thromboxane Biosynthesis and Platelet Function in Type II Diabetes MellitusNew England Journal of Medicine, 1990
- Platelet Activation in Unstable Coronary DiseaseNew England Journal of Medicine, 1986
- Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease.Circulation, 1983