CELLULAR REACTIONS TO PHTHIENOIC ACID AND RELATED BRANCHED-CHAIN ACIDS
- 1 January 1952
- journal article
- research article
- Published by Elsevier
- Vol. 65 (6), 655-672
- https://doi.org/10.1164/art.1952.65.6.655
Abstract
An alpha-beta unsaturated acid of the phthioic type, designated as phthienoic acid, and its saturated analogue, phthianoic acid, were studied for their antituberculous activity. Both of these agents produced epithelioid cells, giant cells, and tubercles. Phthienoic acid inhibited the migration of leukocytes on plasma clot. O2 uptake of leukocytes treated with these 2 acids was not affected.Keywords
This publication has 2 references indexed in Scilit:
- THE PRINCIPAL STRUCTURAL FEATURES OF C27-PHTHIENOIC ACIDJournal of Biological Chemistry, 1951
- INVESTIGATION OF A FRACTION OF ACIDS OF THE PHTHIOIC TYPE FROM THE TUBERCLE BACILLUSJournal of Biological Chemistry, 1951