Pancuronium and Abnormal Abdominal Roentgenograms
- 1 September 1980
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Pediatrics & Adolescent Medicine
- Vol. 134 (9), 821-823
- https://doi.org/10.1001/archpedi.1980.02130210005002
Abstract
• Pancuronium bromide treatment in severely ill, mechanically ventilated infants has been shown to result in lower peak transpulmonary pressures, with an accompanying lower-than-expected incidence of pneumothorax. Infants treated with pancuronium often demonstrate an ominous abdominal roentgenographic finding: the "gasless abdomen." Of 38 mechanically ventilated infants, 22 of 24 pancuronium-treated infants (as compared with four of 14 untreated infants) had diminished or absent bowel gas. There was no significant difference between the two groups with regard to birth weight, mortality, or incidence of respiratory distress syndrome. Pancuronium prevents swallowing of air but does not inhibit gut peristalsis, thus accounting for the evacuation of abdominal gas three hours or more after administration of the drug. Clinicians who treat infants with pancuronium should be aware of the phenomenon, to avoid needless roentgenographic studies. (Am J Dis Child 134:821-823, 1980)This publication has 4 references indexed in Scilit:
- Pancuronium BromidePublished by Qeios Ltd ,2020
- Neonatal gasless abdomen: another causeAmerican Journal of Roentgenology, 1979
- Muscle relaxation in mechanically ventilated infantsThe Journal of Pediatrics, 1979
- Drugs Five Years LaterAnnals of Internal Medicine, 1978