Hormonal response to electrocautery of the ovary in patients with polycystic ovarian disease
- 1 December 1985
- journal article
- research article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 92 (12), 1258-1264
- https://doi.org/10.1111/j.1471-0528.1985.tb04872.x
Abstract
Fifty-eight women with polycystic ovarian syndrome (PCO) were treated with electrocautery of the ovarian capsule and then studied by hormone analysis for 12 months. In 72% ovulation appeared to occur within 4 weeks and in this group mean serum LH and FSH levels showed a statistically significant increase the day after electrocautery, followed by a gradual decline in LH to a level significantly below the pretreatment value. No changes in LH and FSH were seen in those who did not ovulate. The mean levels of testosterone, androstenedione and dihydrotestosterone which were in the upper normal range or slightly above before treatment were significantly reduced after electrocautery. Serum oestradiol levels showed a significant increase after 1 week, when progesterone levels were still unchanged, suggesting that follicular development was already in progress. The mean serum level of sex hormone binding globulin was slightly below the normal range before treatment and then increased gradually. Endocrine responses to electrocautery were similar to those described previously after wedge resection. The simplicity of this treamtent and the good response make it an attractive alternative for treating infertility associated with PCO.This publication has 20 references indexed in Scilit:
- Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscopeFertility and Sterility, 1984
- The effect of sleep deprivation on the plasma levels of hormones during prolonged physical strain and calorie deficiencyEuropean Journal of Applied Physiology, 1982
- Identification of Protein(s) Secreted by the Preovulatory Ovary which Suppresses the Follicle Response to Gonadotropins*Journal of Clinical Endocrinology & Metabolism, 1982
- Folliculogenesis in the Primate Ovarian CycleEndocrine Reviews, 1981
- Hormone Changes in Patients with Prostatic Carcinoma, During Treatment with Estramustine PhosphateJournal of Urology, 1977
- DEMONSTRATION OF AN FSH RECEPTOR IN A FUNCTIONING GRANULOSA CELL TUMOURActa Endocrinologica, 1977
- Circulating gonadotropins, estrogens, and androgens in polycystic ovarian diseaseAmerican Journal of Obstetrics and Gynecology, 1975
- Daily serum follicle-stimulating hormone, luteinizing hormone, and plasma testosterone and androstenedione in hirsute women with polycystic sclerotic ovaries: Effects of diethylstilbestrol and norethindrone acetateAmerican Journal of Obstetrics and Gynecology, 1973
- The Polycystic Ovary. I. Clinical and Histologic FeaturesJournal of Clinical Endocrinology & Metabolism, 1962
- Amenorrhea associated with bilateral polycystic ovariesAmerican Journal of Obstetrics and Gynecology, 1935