A Simple Method for Gas Chromatographic Determination of Lidocaine in Tissues
Open Access
- 1 November 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 47 (5), 466-467
- https://doi.org/10.1097/00000542-197711000-00016
Abstract
A simple gas chromatographic method for the determination of lidocaine (a local anesthetic) in tissues is described. Lidocaine was extracted from dog tissue samples using liquid N. The recoveries of lidocaine from brain, liver and muscle were 98.6, 99.8 and 89.1%, respectively. Results were reproducible to within 1.0% of lidocaine administered.Keywords
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