Proton magnetic resonance studies of the tyrosine residues of hen lysozyme-assignment and detection of conformational mobility
Open Access
- 17 June 1975
- journal article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 189 (1097), 503-509
- https://doi.org/10.1098/rspb.1975.0070
Abstract
This paper reports the detection of all the proton magnetic resonances from the aromatic rings of the three tyrosine residues of hen egg white lysozyme. Procedures, including spin decoupling, for the full assignment of these residues are described. To explain the appearance and behaviour of these resonances it is postulated that the tyrosine rings are able to flip between equivalent conformations at rates exceeding 10$^{4}$ s$^{-1}$.Keywords
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