CO2‐Mediated Control of Fatty Acid Metabolism in Isolated Hamster Brown‐Fat Cells during Norepinephrine Stimulation
Open Access
- 1 January 1977
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 72 (2), 235-240
- https://doi.org/10.1111/j.1432-1033.1977.tb11244.x
Abstract
1 Addition of norepinephrine to isolated hamster brown-fat cells suspended in Krebs-Ringer phosphate buffer induces a pronounced, but temporary, increase in respiratory rate. 2 If Krebs-Ringer phosphate buffer is bubbled with CO2 prior to the addition of cells and norepinephrine, the respiratory capacity of the cells is further potentrated and most important, the respiration is maintained at a high rate until the medium becomes depleted of oxygen. 3 This respiratory pattern cannot be obtained in CO2-bubbled Krebs-Ringer bicarbonate buffer. 4 The results indicate that CO2 has a regulatory effect on fatty acid metabolism in isolated hamster brown-fat cells.This publication has 21 references indexed in Scilit:
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