Evidence for Neuronal Localization of Histamine‐N‐Methyltransferase in Rat Brain
- 1 August 1981
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 37 (2), 525-526
- https://doi.org/10.1111/j.1471-4159.1981.tb00489.x
Abstract
Histamine may be a neurotransmitter in rat brain. Histamine in neurons of the CNS is easily released and rapidly turned over. The cellular localization of histamine-N-methyltransferase, the proposed histamine-inactivating enzyme, was investigated by measuring its activity in rat striatum after applying neurochemical or electrolytic lesions. A major neuronal localization of the enzyme evidently exists in this area.Keywords
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