The Bursicon Gene in Mosquitoes: An Unusual Example of mRNA Trans-splicing
- 1 June 2007
- journal article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 176 (2), 1351-1353
- https://doi.org/10.1534/genetics.107.070938
Abstract
The bursicon gene in Anopheles gambiae is encoded by two loci. Burs124 on chromosome arm 2L contains exons 1, 2, and 4, while burs3 on arm 2R contains exon 3. Exon 3 is efficiently spliced into position in the mature transcript. This unusual gene arrangement is ancient within mosquitoes, being shared by Aedes aegypti and Culex pipiens.Keywords
This publication has 14 references indexed in Scilit:
- Analysis of the complete mitochondrial DNA from Anopheles funestus: An improved dipteran mitochondrial genome annotation and a temporal dimension of mosquito evolutionMolecular Phylogenetics and Evolution, 2006
- A computational investigation of kinetoplastid trans-splicingGenome Biology, 2005
- Efficient in vivo gene expression by trans-splicing adeno-associated viral vectorsNature Biotechnology, 2005
- Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2FEBS Letters, 2005
- Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2Proceedings of the National Academy of Sciences, 2005
- Trans-splicing of the mod(mdg4) Complex Locus Is Conserved Between the Distantly Related Species Drosophila melanogaster and D. virilisGenetics, 2005
- Identification of the Gene Encoding Bursicon, an Insect Neuropeptide Responsible for Cuticle Sclerotization and Wing SpreadingCurrent Biology, 2004
- The Genome Sequence of the Malaria Mosquito Anopheles gambiaeScience, 2002
- A global analysis of Caenorhabditis elegans operonsNature, 2002
- Trans-splicing of pre-mRNA in plants, animals, and protists.The FASEB Journal, 1993