Comparative detoxication. 5. Conjugation of aromatic acids in reptiles: formation of ornithuric acid, hippuric acid and glucuronides

Abstract

Ornithuric acids have been detected as the major amino acid conjugate in the excreta of 6 species of reptile after feeding aromatic acids. L(+)-Ornithuric acid has been isolated from excreta of Testudo graeca and Emys orbicularis dosed with benzoic acid. After p-aminobenzoic acid was fed to Natrix natrix, Lacerta viridis, Testudo graeca and Caiman sp., small amounts of p-aminobenzoylglucuronide were detected in the excreta. After feeding p-aminobenzoic acid, traces of p-aminohippuric acid were found in the excreta of Natrix and Lacerta and large amounts in the excreta of Caiman and Testudo.