ARTIFICIAL STIMULATION AND INHIBITION OF THE GROWTH OF NORMAL AND SARCOMATOUS TISSUES

Abstract

We have studied by the method of cultivation of tissuesin vitro, the properties acquired by the plasma during the development of an experimental malignant tumor. The experiments were performed on chickens of thoroughbred stock, obtained from the same farm, inoculated with the sarcoma propagated by Dr. Peyton Rous. Fragments of this tumor and of normal tissues of chick embryos and adult individuals were cultivated comparatively in the plasma obtained from normal animals and in the plasmas obtained from sarcomatous chickens at different stages of the disease. Sharp differences in the rate and in the dimensions of the growth could easily be observed, even without the use of the microscope. INFLUENCE OF NORMAL AND SARCOMATOUS PLASMAS ON THE GROWTH OF SARCOMATOUS TISSUES Sarcoma cultivated in the plasma of the individual bearing the tumor grew very extensively. The area covered by the new cells in twenty-four hours was often fifteen or