AMINO ACID COMPOSITION OF AMNIOTIC FLUID IN INTRAHEPATIC CHOLESTASIS OF PREGNA4NCY, PRE‐ECLAMPSIA AND RHESUS INCOMPATIBILITY
- 1 October 1975
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 82 (10), 786-789
- https://doi.org/10.1111/j.1471-0528.1975.tb00574.x
Abstract
The levels of free amino acids in amniotic fluid were determined in twenty patients with normal pregnancy, five with intrahepatic cholestasis of pregnancy, twelve with pre-eclampsia, and four with rhesus incompatibility. In pre-eclampsia there was no significant change in the amino acid composition of the amniotic fluid. In recurrent intrahepatic cholestasis the concentration of 15 out of the 22 amino acids studied was significantly higher than normal and the mean concentration of 4 others was more than 20 per cent above normal without this being statistically significant. In rhesus incompatibility there was a significant decrease in the concentration of 13 amino acids, and a decrease of more than 20 per cent in the mean concentration of 5 others.Keywords
This publication has 11 references indexed in Scilit:
- Concentrations of the free amino acids in human amniotic fluid during normal and abnormal pregnanciesAmerican Journal of Obstetrics and Gynecology, 1974
- AMINOACID COMPOSITION OF AMNIOTIC FLUID IN CENTRAL- NERVOUS-SYSTEM MALFORMATIONSThe Lancet, 1973
- Amino acid variations in amniotic fluid and maternal plasma from Rh-sensitized pregnanciesAmerican Journal of Obstetrics and Gynecology, 1972
- Gas chromatographic analysis of concentrations of amino acids in amniotic fluid from early, middle, and late periods of human gestationAmerican Journal of Obstetrics and Gynecology, 1972
- Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancyAmerican Journal of Obstetrics and Gynecology, 1971
- THE INFLUENCE OF PRE‐ECLAMPSIA AND DIABETES MELLITUS ON PLASMA FREE AMINO ACIDS IN MATERNAL, UMBILICAL VEIN AND INFANT BLOODBJOG: An International Journal of Obstetrics and Gynaecology, 1971
- Quantitative Cation-Exchange Chromatographic Analysis of Free Amino Acids in Human Amniotic Fluid Collected during Early PregnancyClinical Chemistry, 1970
- Amniotic fluid proteins in normal and Rh-sensitized pregnanciesAmerican Journal of Obstetrics and Gynecology, 1970
- Free Amino-acid Concentrations in Fetal FluidsBMJ, 1970
- ANTENATAL DIAGNOSIS AND AMINOACID COMPOSITION OF AMNIOTIC FLUIDThe Lancet, 1970