THE CRYSTAL STRUCTURE OF AN INTERMOLECULAR NUCLEOSIDE COMPLEX: ADENOSINE AND 5-BROMOURIDINE

Abstract

The crystal structure of an inter molecular complex containing adenosine and 5-bromouridine has been presented. The results demonstrate the existence of a third type of base pairing which is different from that occurring in DNA as hypothesized by Watson and Crick and that found by Hoogsteen in a crystal complex of 9-methyl adenine and 1-methyl thy mine. The significance and possible biological implications of this new structure are discussed briefly.