CEREBROSPINAL FLUID
- 1 April 1948
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Neuropathology and Experimental Neurology
- Vol. 7 (2), 172-181
- https://doi.org/10.1097/00005072-194804000-00005
Abstract
The author disagrees with orthodox views and concludes that the cerebrospinal fluid represents the tissue fluids of the brain; it is an actual lymph of the central nervous system, for it carries away its waste. The adventitial spaces of Virchow-Robin are the principal, if not the only source of cerebrospinal fluid, and they discharge into the cerebral ventricles and subarachnoid spaces. The function of the choroid plexus is not to secrete fluid but to excrete or eliminate from it noxious substances and to make it absorbableby the perineurial spaces. The absorption of the fluid is not through the villi or pacchionian bodies, but through the perineurial spaces of the cranial nerves ana spinal roots. There is no central force that sets the cerebrospinal fluid in circulation. The power that manipulates the removal of spinal fluid is the collapsing and expanding movement of the brain and spinal cord. The hemato-encephalic barrier (if such exists) is in the Virchow-Robin spaces.Keywords
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