Synthesis of the hexadecapeptide corresponding to positions 1 through 16 of porcine motilin, a gastric motor activity stimulating polypeptide.

Abstract

The hexadecapeptide corresponding to positions 1 to 16 of porcine motilin was synthesized in a conventional manner. The synthetic peptide exhibited the activity of 3% of that of the synthetic motilin, when tested using rabbit duodenal muscle in vitro.