During the past year the use of aminophylline intravenously in cases of cardiac failure and in bronchial asthma when epinephrine and other remedies are ineffectual has been frequently reported. That the results are often most satisfactory is true. That its use is also not without danger is also true, as a recital of the following cases will demonstrate: REPORT OF CASES M. G., a man aged 52, whose previous history was irrelevant, was pronounced normal as the result of a hospital check-up, including an electrocardiogram, twelve months ago. At 2 p. m., while finishing luncheon, he was seized with severe precordial pain. The hotel physician on examining him made a diagnosis of acute coronary closure, and, feeling that he was too ill for removal to a hospital, had him carried to a room, where he was put to bed. When I saw him, at 6 p. m., he was still