Substance SC (ubichromenol): a naturally-occurring cyclic isomeride of ubiquinone-50
- 1 March 1960
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 74 (3), 541-549
- https://doi.org/10.1042/bj0740541
Abstract
A normal minor unsaponifiable lipid, hitherto designated substance SC, and present in kidney and other tissues of many species, has been isolated from normal human kidney, its concentration in this tissue being about 10 mg/kg. Substance SC is a yellow crystalline compound, melting point about 18[degree]. It is isomeric with ubiquinone, C59H90O4, but is not itself a quinone. Substance SC contains a chromene ring system and a large polyisoprenoid side chain. Perhydro-SC can be oxidized by ferric chloride to perhydroubiquinone. Substance SC is therefore a cyclic isomeride of ubiquinone, the cycliza-tion involving the first isoprenoid unit of the side chain and the adjacent oxygen function. The name ubichromenol is suggested for substance SC.Keywords
This publication has 13 references indexed in Scilit:
- Unsaponifiable fraction of lipid from normal and diseased human kidneyBiochemical Journal, 1959
- Internal Distribution of Coenzyme Q in Higher Plants.Plant Physiology, 1959
- UbiquinoneNature, 1958
- Ubiquinone and tocopherylquinoneBiochimica et Biophysica Acta, 1958
- The possible rôle of α-tocopherol in the respiratory chain I. The identification and quantitative determination of α-tocopherol in respiratory chain preparationsBiochimica et Biophysica Acta, 1957
- Aspects of vitamin A deficiency in the ratBiochemical Journal, 1957
- Isolation of a quinone from beef heart mitochondriaBiochimica et Biophysica Acta, 1957
- The vitamin A-deficiency syndrome in the rat.1955
- Unsaponifiable fractions from kidneys and livers of various species.1955
- Aspects of Vitamin a Deficiency in RatsNature, 1953