Reduction of X-Ray Lethality in Mice by Agents Affecting the Reticuloendothelial System

Abstract
Mortality of mice irradiated several weeks after administration of B.C.G. and zymosan was significantly reduced. There was no accelerated recovery of hemopoietic and lymphatic tissue. Certain enhanced activities of the RES related to increased nonspecific resistance were still evident after lethal irradiation. A correlation between resistance to near-lethal irradiation and the functional state of RES phagocytic elements is postulated.