The Transcription Factor NF‐κB Mediates Increases in Calcium Currents and Decreases in NMDA‐ and AMPA/Kainate‐Induced Currents Induced by Tumor Necrosis Factor‐α in Hippocampal Neurons

Abstract

Tumor necrosis factor-α (TNFα) is a cytokine rapidly produced in the brain in response to vigorous neuronal activity and tissue injury. TNFα may protect neurons against excitotoxic and oxid...