PAPER ELECTROPHORESIS OF SERA AND PLASMA FROM CHICKS AFFECTED WITH ERYTHROBLASTOSIS

Abstract

Plasma and sera from normal and leukemic (erythroblastosis) chickens have been studied with the aid of paper electrophoresis. Differences are more easily demonstrable with pH 6.4 phosphate buffer than with barbiturate buffer. There is a relative depression in serum albumin and an apparent 'shift' in the positions normally occupied by the α- and β-globulins. The latter regularly appear to move as one band in electropherograms of sera from leukemic birds. It has been possible to induce this 'shift' in normal sera by storage or incubation.