Decreased Accumulation of Phthalate Plasticizer during Storage of Blood as Packed Cells
- 2 January 1977
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 17 (1), 71-72
- https://doi.org/10.1046/j.1537-2995.1977.17177128891.x
Abstract
Accumulation of phthalate plasticizer (di-(2-ethyl-hexyl) phthalate, DEHP) [from polyvinyl containers] was markedly reduced in blood [human] stored as packed cells rather than as whole blood. After the 1st wk, the accumulation rate in whole blood was essentially linear but in packed cells, DEHP accumulation was lower, and reached a plateau. At 3 wk whole blood contained about 3 times more DEHP than did packed cells. Smaller amounts of plasma and restricted diffusion probably limited DEHP accumulation in packed cell preparations.This publication has 4 references indexed in Scilit:
- Accumulation of DI‐2‐Ethylhexyl Phthalate (DEHP) in Whole Blood, Platelet Concentrates, and Platelet‐Poor PlasmaTransfusion, 1974
- Metabolism of diethylhexyl phthalate by ratsJournal of Chromatography A, 1973
- Extraction, localization, and metabolism of di-2-ethylhexyl phthalate from PVC plastic medical devices.Environmental Health Perspectives, 1973
- Migration of a Phthalate Ester Plasticizer from Polyvinyl Chloride Blood Bags into Stored Human Blood and Its Localization in Human TissuesNew England Journal of Medicine, 1972