Use of 1,3-dioxin-4-ones and related compounds in synthesis. Part 37. 5-Trifluoromethyl-1,3-dioxin-4-ones as versatile building blocks for trifluoromethylated aliphatic compounds

Abstract

Synthesis of 5-trifluoromethyl-1,3-dioxin-4-ones and their use for the preparation of a variety of trifluoromethylated aliphatic compounds are described. Their usefulness has been demonstrated either by the formation of α-trifluoromethyl-β-keto esters via the corresponding acylketenes or by their direct participation in pericyclic reactions as a _π2 component.