People with Down's syndrome can be distinguished on the basis of cholinergic dysfunction.
Open Access
- 1 November 1989
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 52 (11), 1294-1295
- https://doi.org/10.1136/jnnp.52.11.1294
Abstract
The mydriatic response to eyedrops of the anticholinergic agent tropicamide at very low concentration (0.01%) has been studied in people with Down's syndrome. By comparison with healthy subjects people with Down's syndrome had responses approximately three times greater, suggesting a peripheral imbalance between cholinergic and adrenergic autonomic influences.This publication has 13 references indexed in Scilit:
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