On the Specificity and Differentiation of Cholinesterases.

Abstract

The ability to hydrolyze noncholine esters can no longer be used as a criterion to distinguish the two cholinesterase types, since both groups of enzymes are able to split noncholine esters; for example, ethyl chloroacetate. Another noncholine ester, β-chloroethyl acetate, is even preferentially attacked by the e-type (“true” or “specific” ChE).