Cerebral abscesses produced by bacterial implantation and septic embolisation in primates.
Open Access
- 1 January 1979
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 42 (1), 63-69
- https://doi.org/10.1136/jnnp.42.1.63
Abstract
The degree of brain abscess encapsulation is positively related to surgical mortality and methods to enhance capsule wall formation, therefore, have therapeutic relevance. Two primate models are described which may be useful in the investigation of encapsulation of traumatic and metastatic brain abscesses. Direct intracerebral inoculation induces abscesses displaying more prominent inflammatory responses and encapsulation than does septic embolisation, despite similar abscess age and size. Cerebral ischaemia surrounding metastatic suppurative foci may retard capsule wall formation.This publication has 30 references indexed in Scilit:
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