Correct Axonal Regeneration After Target Cell Removal in the Central Nervous System of the Leech
- 5 October 1979
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4414), 87-89
- https://doi.org/10.1126/science.482931
Abstract
The unique target neuron of a severed axon in the leech was selectively eliminated by intracellular injection of protease. In the absence of the target, the severed axon regenerated normally along its original pathway to the usual site of synapse, where it stopped growing without forming alternative connections.Keywords
This publication has 17 references indexed in Scilit:
- Physiological properties of the innervated and denervated neuromuscular junction of hibernating and nonhibernating ground squirrelsExperimental Neurology, 1978
- Directed outgrowth of optic fibres regenerating in vitroNature, 1978
- Growing central axons deprived of normal target neurones by neonatal X-ray irradiation still terminate in a precisely laminated fashionNature, 1977
- Evidence for the glia-neuron protein transfer hypothesis from intracellular perfusion studies of squid giant axons.The Journal of cell biology, 1977
- Initial endocytosis of peroxidase or ferritin by growth cones of cultured nerve cellsJournal of Neurocytology, 1977
- A regenerating neurone in the leech can form an electrical synapse on its severed axon segmentNature, 1977
- Axonal guidance of developing optic nerves in the frog. I. Anatomy of the projection from transplanted eye primordiaJournal of Comparative Neurology, 1976
- A multisomatic axon in the central nervous system of the leechJournal of Comparative Neurology, 1975
- Behavioral manifestations of competition of retinal endings for sites in doubly innervated frog optic tectumExperimental Neurology, 1974
- Orientation and directed growth of Mauthner's cell axons from duplicated vestibular nerve rootsExperimental Neurology, 1965