Abnormalities of Urogenital System in Strain A x C Line 9935 Rats

Abstract

The occurrence of congenital abnormalities of the urogenital system of strain A x C line 9935 rats has been described. The principal manifestations were the absence of one kidney or the presence of one cystic kidney. These were accompanied generally by other abnormal conditions. In females, they included a missing ureter, uterine horn, oviduct, ovarian capsule, or ovary; an incomplete ureter or uterine horn; a cystic ureter, uterine horn, or ovarian capsule: or hypertrophy of the remaining kidney, with variation in degree of abnormality. In males, they included a missing ureter, epididymis, vas deferens, or vesicular gland; atrophy of the testis, vesicular gland, or epididymis: cystic ureter; undescended testis; and hypertrophy of the remaining kidney, all also varying in degree.