Multiple genes for G protein‐coupled receptors and their expression in lingual epithelia
- 1 February 1993
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 316 (3), 253-256
- https://doi.org/10.1016/0014-5793(93)81302-g
Abstract
Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein‐coupled seven‐transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.Keywords
This publication has 21 references indexed in Scilit:
- A novel multigene family may encode odorant receptors: A molecular basis for odor recognitionCell, 1991
- The sweet taste inhibitor methyl 4,6-dichloro-4,6-dideoxy-α-D-galactopyranoside inhibits sucrose stimulation of the chorda tympani nerve and of the adenylate cyclase in anterior lingual membranes of ratsChemical Senses, 1990
- Selective Amplification And Cloning Of Four New Members Of The G Protein-coupled Receptor FamilyScience, 1989
- Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red PigmentsScience, 1986
- Norepinephrine as a possible transmitter involved in synaptic transmission in frog taste organs and Ca dependence of its release.The Journal of general physiology, 1985
- Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segmentNature, 1985
- Inositol trisphosphate, a novel second messenger in cellular signal transductionNature, 1984
- Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsinCell, 1983
- Regenerative Impulses in Taste CellsScience, 1983
- Human Taste: Response and Taste Bud Number in Fungiform PapillaeScience, 1980