Gonadotrophic Activity of Granules Isolated from Rat Pituitary Glands.
- 1 July 1949
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 71 (3), 407-410
- https://doi.org/10.3181/00379727-71-17206
Abstract
Approx. 60% of the succinoxidase activity of rat pituitary glands was found to be associated with the large granule fraction, and more than 50% of the gonadotropin of these glands was associated with 2 granule fractions isolated from sucrose homogenates by differential centrifugation. The supernatant fraction from which the granules were removed contained the remaining gonadotropic activity. The gonadotropin can be extracted from the isolated granules with isotonic NaCl soln.Keywords
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