THE EFFECT OF ROENTGEN RAY IRRADIATION ON NORMAL, HYPOTHYROID AND HYPERTHYROID RATS1

Abstract

Thyroparathyroidec-tomy does not significantly increase the survival time nor decrease the total mortality of X-irradiated rats. Thyroxine increased mortality rate as compared to normal and hypothyroid animals, even though there are no significant differences in total mortality. Under the same conditions thyroglobulin does not produce any significant difference in the rate of mortality. Thyroxine and thyroglobulin premedication of hypothyroid rats decreases their survival time but not their total mortality as compared to non-medicated hypothyroid and normal animals.