Unique and repetitive sequences in multiple genes for feather keratin
- 1 April 1975
- journal article
- Published by Springer Nature in Nature
- Vol. 254 (5501), 573-577
- https://doi.org/10.1038/254573a0
Abstract
Embryonic chick feather keratins are a family of homologous polypeptide chains. The mRNA coding for these has been obtained in a pure state and transcribed into complementary DNA (cDNA) using the reverse transcriptase from avian myeloblastosis virus. Studies on the kinetics of hybridisation and reannealing of cDNA indicate that there are 25-35 different keratin mRNA species in the embryonic chick feather, and a total of 100-240 keratin genes in the chick genome. Each keratin gene contains both a unique and a repetitive sequence. It is proposed that the repetitive sequences are the keratin coding sequences and that the unique sequences correspond to untranslated regions.Keywords
This publication has 44 references indexed in Scilit:
- Isolation and molecular weight of pure feather keratin mRNABiochemical and Biophysical Research Communications, 1974
- Interspersion of repetitive and non-repetitive DNA sequences in the sea urchin genomeCell, 1974
- Comparative hybridization studies with an immunoglobulin light chain mRNA fraction and non‐immunoglobulin mRNA of mouseFEBS Letters, 1974
- Reduction in the rate of DNA reassociation by sequence divergenceJournal of Molecular Biology, 1973
- Reiterated transfer RNA genes of Xenopus laevisJournal of Molecular Biology, 1973
- A multiple promoter model for transcriptional control in differentiated organismsJournal of Theoretical Biology, 1973
- General interspersion of repetitive with non-repetitive sequence elements in the DNA of XenopusJournal of Molecular Biology, 1973
- The genes for silk fibroin in Bombyx moriJournal of Molecular Biology, 1972
- A comparison of the ribosomal DNA's of Xenopus laevis and Xenopus mulleri: the evolution of tandem genesJournal of Molecular Biology, 1972
- On the structural organization of operon and the regulation of RNA synthesis in animal cellsJournal of Theoretical Biology, 1969