EFFECTS OF SYMPATHOMIMETIC AMINES ON 45Ca EFFLUX FROM LIVER SLICES
Open Access
- 1 May 1976
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 57 (1), 158-160
- https://doi.org/10.1111/j.1476-5381.1976.tb07668.x
Abstract
The efflux of 45Ca from slices of guinea-pig and rabbit liver is greatly increased by α-adrenoceptor agonists. Isoprenaline is much less effective. The effects of these agents on the efflux of 45Ca mirror their actions on 42K loss and suggest that the two may be related. Glucose release from both rabbit and guinea-pig liver slices is increased to a similar extent by either α- or β-receptor agonists. The possible relationship between Ca and K movements and the production of glucose is discussed.Keywords
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