Enzymatic replication of E. coli chromosomal origin is bidirectional
- 15 April 1982
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 296 (5858), 623-627
- https://doi.org/10.1038/296623a0
Abstract
A soluble enzyme system has been discovered which specifically recognizes and replicates plasmids containing the Escherichia coli chromosomal origin, oriC. Electron microscopy has shown that plasmid replication begins at or near oriC from which it progresses bidirectionally to completion. Control of initiation of a cycle of chromosomal replication and mechanisms of priming and fork movement can now be explored using this system.This publication has 33 references indexed in Scilit:
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