Electrophysiological study of the peripheral and central neurotoxic effect of cis-platin
- 31 July 1987
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 76 (2), 86-93
- https://doi.org/10.1111/j.1600-0404.1987.tb03551.x
Abstract
We describe clinical and electrophysiological findings in 8 patients with tumors of germ cell origin before and after treatment with high-dose cisplatin (800–1400 mg) combined with etoposide and bleomycin. All patients developed clinical or electrophysiological signs, or both, of a peripheral sensory neuropathy. One had in addition clinical and electrophysiological signs of CNS involvement, and 2 had a central conduction defect revealed by auditory stimulation.This publication has 23 references indexed in Scilit:
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