Constitutive production of angiotensin converting enzyme from rheumatoid nodule cells under serum free conditions.
Open Access
- 1 June 1992
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 51 (6), 741-742
- https://doi.org/10.1136/ard.51.6.741
Abstract
Angiotensin converting enzyme was assayed in serum free culture supernatants from unstimulated rheumatoid nodule cells. Angiotensin converting enzyme was released spontaneously and the angiotensin converting enzyme derived from rheumatoid nodule cells was suppressed in a dose and time dependent manner by the protein synthesis inhibitor cycloheximide. These data suggest the constitutive de novo synthesis of angiotensin converting enzyme by rheumatoid nodule cells.This publication has 13 references indexed in Scilit:
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