The use of sulpharsphenamine injected intramuscularly in the treatment of warts was reported in October, 1926, by Sutton.1 He noted that a crop of verrucae planae juveniles disappeared while a patient was being given the drug for another purpose. Subsequently he used it with uniform success in five other cases in which this type of wart occurred. In 1931, Osborne and Putnam2 reported that of 40 patients whom they treated with this preparation, 20 were cured and 20 were not, but these investigators made no discrimination as to the type of verrucae under treatment. Accordingly, it was proposed by Dr. MacKee that an attempt be made to evaluate this form of therapy more accurately. A series of patients was given sulpharsphenamine, dissolved in distilled water and injected intramuscularly into the gluteal muscles. The dosage ranged from 0.1 to 0.3 Gm., according to the age and the weight of