Sequencing of Neisseria meningitidis penA Gene: the Key to Success in Defining Penicillin G Breakpoints
- 1 January 2004
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (1), 358-9
- https://doi.org/10.1128/aac.48.1.358-359.2004
Abstract
Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the penA gene were done for 43 meningococcal strains. Those strains for which the MIC was ≥0.094 μg/ml showed mosaic alleles, so 0.094 μg/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.Keywords
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