An Unstable Liaison
- 18 April 2003
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 300 (5618), 442-443
- https://doi.org/10.1126/science.1084468
Abstract
It is well established that changes in the pattern of DNA methylation are involved in tumor formation. But whether hypomethylation or hypermethylation is the culprit is questionable. In his Perspective, Lengauer discusses intriguing new findings providing evidence that hypomethylation contributes to genomic instability leading to cancer.Keywords
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