THE PRODUCTION OF AEROSOLS FROM MEDICATED SOLUTIONS

Abstract

Aerosol of penicillin, as advocated by Barach after Bryson's preliminary observations, is finding increasing use in the treatment of diseases of the upper and lower respiratory tracts. The method described by Barach consists in a special nebulizer containing concentrated solutions of penicillin in saline solution. Oxygen flowing through the nebulizer produces an aerosol of penicillin which can then be inhaled. To conserve the penicillin a rebreathing bag as well as a Y tube has been inserted into the circuit. The oxygen here is used primarily as a driving force. This led to the use of a cheaper source of power, namely, steam, and it was possible to convert a device originally designed for the dispersion of solutions of insecticide for the purpose of producing medicated aerosols. To this apparatus has been added a valve for controlling the onset and rate of production of the aerosol. The apparatus consists of a