IN VITRO DETOXIFICATION OF BACTERIAL ENDOTOXIN BY MACROPHAGES

Abstract

Macrophages in vitro with normal serum or plasma detoxify endotoxin. Partial detoxification is achieved by serum or plasma alone. Comparison of data indicates that immune serum is more potent than normal serum, that macrophages in immune serum are more potent than immune serum alone, and that granulocytes are less potent than macrophages.