A Pressor Substance in the Cerebrospinal Fluid of Normotensive and Hypertensive Patients
- 1 November 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (11), 3341-3344
- https://doi.org/10.1073/pnas.69.11.3341
Abstract
A pressor polypeptide was isolated from the cerebrospinal fluid of normotensive and hypertensive patients. Pharmacologically it behaves like angiotensin I. A very significant correlation (r = 0.83, P < 0.001) was found between the concentration of this polypeptide and the blood pressure of essential hypertensive patients.Keywords
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