Circulating Proinsulin-like Material in Patients with Functioning Insulinomas
- 6 May 1971
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 284 (18), 1003-1008
- https://doi.org/10.1056/nejm197105062841803
Abstract
Because islet-cell tumors of the pancreas produce proinsulin-like material in vitro, the plasma of 11 patients with functioning insulinomas was studied to determine the immunoreactive insulin proportion contributed by circulating proinsulin-like material.Keywords
This publication has 14 references indexed in Scilit:
- Proinsulin Secretion by a Pancreatic Beta-Cell AdenomaNew England Journal of Medicine, 1970
- Effect of Streptozotocin on Qualitative Aspects of Plasma Insulin in a Patient with a Malignant Islet Cell TumorJournal of Clinical Endocrinology & Metabolism, 1970
- Synthesis and Release of Proinsulin and Insulin by Human Insulinoma TissueJournal of Clinical Endocrinology & Metabolism, 1970
- Human serum proinsulinJCI Insight, 1970
- Plasma insulin: fluctuations in the “big” insulin component in man after glucose and other stimuliJCI Insight, 1969
- Circulating insulins. "Big" and "little"Archives of Internal Medicine, 1969
- "Big insulin": a new component of plasma insulin detected by immunoassay.Proceedings of the National Academy of Sciences, 1968
- THE BIOSYNTHESIS OF INSULIN AND A PROBABLE PRECURSOR OF INSULIN BY A HUMAN ISLET CELL ADENOMAProceedings of the National Academy of Sciences, 1967
- Plasma Insulin in Organic Hyperinsulinism: Comparative Effects of Tolbutamide, Leucine and Glucose1Journal of Clinical Endocrinology & Metabolism, 1964
- The isolation of insulin from a single cat pancreasBiochimica et Biophysica Acta, 1962